WHAT TO TRY FIRST
The 2014 International Viral Society USA Panel recommends antiretroviral therapy for all adults when first diagnosed with HIV - regardless of CD4 counts.
The goal of treatment is to keep HIV viral loads undetectable.
The Society recommends starting with 2 nucleoside reverse transcriptase inhibitors (NRTIs: abacavir/lamivudine or tenofovoir/emtricitabine) and a third single or boosted drug (an integrase strand transfer inhibitor (dolutegravir, elvitegravir or raltegravir), a nonnucleoside reverse transcriptase inhibitor (efavirenz or rilpivirine) or a boosted protease inhibitor (darunavir or atazanavir)).
Drugs should be picked or changed based on virus resistance test results - and based on pill burden (how many and how often), side effects, other medical conditions and interactions with other drugs.
WHAT ELSE TO TRY
Depending on response, side effects and personal preferences, different combinations of drugs may be recommended.
International Antiviral Society - USA Panel. Antiretroviral Treatment of Adult HIV Infection. Published July 2014.