WHAT TO TRY FIRST
The Department of Veterans Affairs/Department of Defense recommends as first-choice treatments for osteoarthritis.
In a 2015 systematic look at the evidence for all treatments found:
WHAT ELSE TO TRY
If 1 approach does not work, combining approaches or switching treatments may be helpful.
Department of Veteran Affairs/Department of Defense. VA/DoD Clinical Practice Guideline for the non-surgical management of hip and knee osteoarthritis. Published 2014.
Annals of Internal Medicine. Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: A systematic review and network meta-analysis. Published January 2015.