In type 2 diabetes, the pancreas produces enough insulin, at least in the early years of the disease. But for reasons that are still not well understood, the body’s cells become resistant or insensitive to it. As a result, the telltale marker — and problem — of diabetes emerges: glucose levels rise in the blood because it is unable to enter the body’s cells. The excess glucose is damaging to the body’s tissue and leads to the symptoms and complications of diabetes.
To help control blood sugar in adults with type 2 diabetes
Who might consider taking it?
Adults with type 2 diabetes whose blood sugar is not controlled by diet and exercise. Actos is NOT for treatment of type 1 diabetes or diabetic ketoacidosis.
What is not known
There is no evidence showing that Actos reduces your chance of stroke, heart attack, or vascular disease
Not tested in children younger than 18 years
The effect of Actos on babies during pregnancy is unknown. If you are pregnant or plan to become pregnant, talk with your doctor about the best way to control your blood sugar while you are pregnant.
LONG TRACK RECORD
Long track record means that new‚ unexpected side effects are unlikely. Actos was approved by FDA in 1999. Since Actos has now been used by large numbers of people over a long time‚ the emergence of rare but serious side effects is less likely than with new drugs.
No FDA-required studies at approval
Do not take if you...
Have severe heart failure
Have type 1 diabetes
Have diabetic ketoacidosis (increased ketones in blood or urine)
Are allergic to Actos
Not recommended if you...
Have heart failure with symptoms (shortness of breath or swelling)
Are currently being treated for bladder cancer
Some studies suggest that Actos may increase the chance of bladder cancer. The chance is higher with longer use.
Are younger than 18
Not tested so benefits and harms are unknown
Safe if pregnant or breastfeeding?
Only take if potential benefits outweigh potential harm to baby (FDA Category C)
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This information is meant to enhance communication with your health care provider, not replace it. The content here is meant to educate consumers on health care and medical issues that may affect their daily lives. Nothing in this content should be considered or used as a substitute for medical advice, diagnosis or treatment, or constitute the practice of any medical or other professional health care advice. You should always talk to your health care provider for diagnosis and treatment, including your specific medical needs. This product does not represent or warrant any particular service or product is safe, appropriate or effective for you. See terms for more details.