Celebrex

Celecoxib

For Osteoarthritis

Track record

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Long (approved in 1998)

Special FDA warning?

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Yes - FDA requires black box warning

Bottom line

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Osteoarthritis

What is Osteoarthritis?

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Osteoarthritis is a painful condition in which joints become swollen and stiff.

Other treatments for Osteoarthritis

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Non-drug

Over-the-counter

Prescription

TABLE OF CONTENTS

Overview

FDA-approved use

To treat osteoarthritis

Who might consider taking it?

Adults bothered by pain from osteoarthritis - pain, swelling in hands, knees, hips, spine or other joints from wear and tear

What is not known

No specific issues

Track record

Long track record means that new, unexpected side effects are unlikely.

Celebrex was approved by FDA in 1998. Since Celebrex has now been used by large numbers of people over a long time, the emergence of rare but serious side effects is less likely than with new drugs.

Open questions

NO ONGOING STUDIES

Do not take if you...

Had an asthma attack, hives, or allergic reaction with aspirin or any other NSAID

Are allergic to Celebrex, other NSAID or sulfonamides

Are about to have or have just had heart bypass surgery

Safe if pregnant or breastfeeding?

Pregnant

Up to 30th week of pregnancy: Only take if potential benefits outweigh potential harm to baby (FDA Category C). Beyond 30th week of pregnancy: Only take if needed for life-threatening problem or no safer alternative. Human studies shows Celebrex can harm baby (FDA Category D).

Breastfeeding

Be cautious about breastfeeding - Celebrex gets into breast milk

NEXT: TRIALS

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